Can We Consider PR Interval to Screen Patients for Cardiac Resynchronization Therapy?

How should we optimize cardiac resynchronization therapy?

Optimization of cardiac resynchronization therapy is increasingly performed. Numerous methods have been proposed, many being echocardiographic. Both the technique and the timing of optimization are contentious. Whether acute haemodynamic benefits translate into long-term improvements in remodelling, symptoms, or prognosis is unknown. Recent guidelines from the American Society of Echocardiograp...

Can cardiac resynchronization therapy cause harm?

Most beneficial and effective therapies also have the potential to cause harm. Cardiac resynchronization therapy (CRT) is now proven by large-scale clinical trials to be highly beneficial for chronic heart failure patients, with reduction in mortality and re-hospitalization, and improved quality of life. However, it does have potential adverse effects such as those associated with any pacemaker...

Contribution to the V-V interval optimization in patients with cardiac resynchronization therapy.

The present study proposed procedure for predicting an optimal left and right ventricular pacing interval delay (V-V interval). In 16 patients (heart failure, left bundle branch block, biventricular pacing) two methods (A and B) identifying optimal V-V interval were tested. Method A: predicted optimal V-V interval A (POVV-A) = electromechanical delay of the segment paced by left ventricle lead ...

Superresponse to cardiac resynchronization therapy.

C ase presentation: A 55-year-old female patient underwent implan-tation of a cardiac resynchronization therapy (CRT) defibrillator 6 years ago owing to nonischemic dilated cardio-myopathy. Her left-ventricular (LV) ejection fraction (EF) was 28% before implantation, her LV end-diastolic volume index (EDVI) was 144 mL/m 2 , and her LV end-systolic volume index (ESVI) was 104 mL/m 2. Her intrins...

Cardiac Simulation to Personalize Cardiac Resynchronization Therapy.